Lazio is characterized by its volcanic origins, particularly in areas like the Castelli Romani and around Lake Bolsena. These volcanic soils are rich in minerals, providing an ideal environment for vine cultivation. The nutrients in the soil contribute to the distinct flavors and high quality of the wines produced in these regions.

The eastern part of Lazio is bordered by the Apennine Mountains. These mountains influence the climate by providing cooler temperatures and higher altitudes, which are beneficial for certain grape varieties. The Apennines also contribute to the region’s diverse microclimates.