/bifˈɛrno/
- Molise
- Vineyard Area: 49,62 Hectares
- Year Appellation Started: 1983
- Appellation Last modified: 2014
- Red Grapes: Aglianico, Montepulciano
- White Grapes: Trebbiano Toscano
- White (Bianco)
- Rosso (Red)
- Rosato
- Still White Wine: 70-80% Trebbiano Toscano + 20-30% other white grape varieties allowed for cultivation in the region.
- Still Red Wine: 70-80% Montepulciano + 10-20% Aglianico + maximum 20% other red non-aromatic grape varieties allowed for cultivation in the region.
- Total Production: 3.856 Hectolitres
- White Wine: N/A
- Rose Wine: N/A
- Red Wine: N/A
- Biferno DOC is a relatively lesser-known but fascinating wine appellation located in the Molise region of Southern Italy. Named after the Biferno River, which flows through the region.